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Belatacept Side Effects

The most commonly reported side effects of belatacept include off label use, death, and transplant rejection, based on 4,546 FDA adverse event reports from 2005 to 2025. 4.2% of reports found the drug to be ineffective.

Belatacept side effects

Percentages show how often each reaction appears relative to total reports for belatacept.

1
Off Label Use9.3%423
2
Death5.0%228
3
Transplant Rejection4.9%225
4
Kidney Transplant Rejection4.6%211
5
Drug Ineffective4.2%191
6
Cytomegalovirus Infection3.8%172
7
Acute Kidney Injury3.8%172
8
Product Storage Error3.6%165
9
Covid-193.3%149
10
Hospitalisation2.7%125
11
Pyrexia2.2%100
12
Thrombotic Microangiopathy2.1%95
13
Post Transplant Lymphoproliferative Disorder2.1%95
14
Diarrhoea2.0%89
15
Intentional Product Use Issue1.9%86

These are voluntary reports and do not establish that belatacept caused these reactions.

Report severity

77.5%Serious3,524 reports
38.9%Hospitalizations1,770 reports
16.4%Fatal745 reports

Seriousness is determined by the reporter, not by OpenClaim.

Belatacept drug interactions

Other drugs that appear in adverse event reports alongside belatacept. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Mycophenolate29.1%1,321
2
Prednisone21.7%987
3
Tacrolimus16.9%769
4
Methylprednisolone5.3%243
5
Prednisolone5.0%227
6
Basiliximab3.6%162
7
Sirolimus2.9%132
8
Cyclosporine2.7%125
9
Azathioprine2.6%116
10
Everolimus2.5%114
11
Ganciclovir2.0%90
12
Rituximab2.0%89
13
Eculizumab1.8%80
14
Sulfamethoxazole1.7%77
15
Trimethoprim1.5%70

Taken alongside

1
Prednisone11.9%543
2
Mycophenolate10.6%484
3
Tacrolimus5.7%261
4
Ganciclovir4.4%202
5
Aspirin3.8%171
6
Sulfamethoxazole3.6%163
7
Amlodipine3.5%159
8
Insulin3.5%158
9
Trimethoprim3.3%150
10
Atorvastatin-calcium3.2%144
11
Methylprednisolone3.1%142
12
Metoprolol2.6%117
13
Omeprazole2.6%117
14
Furosemide2.5%113
15
Acetaminophen2.4%107

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports belatacept side effects

31.1% of belatacept adverse event reports involve female patients and 43.8% involve male patients. The largest age group is adult at 67%. These figures reflect who reports side effects, not underlying risk.

Sex

Female31.1%
Male43.8%
Unknown25.1%

Age group

< 20.5%
2–110.2%
12–171.5%
18–6467.5%
65+30.2%

What is belatacept used for

Conditions and purposes for which patients were taking belatacept when the adverse event was reported.

Adenocarcinoma GastricAdverse EventAplastic AnaemiaAtypical Haemolytic Uraemic SyndromeAbdominal DiscomfortAcute Kidney InjuryAtrioventricular Block CompleteAtypical Haemolytic Uraemic SyndromeBlood Immunoglobulin GC3 GlomerulopathyChronic Kidney DiseaseComplications Of Transplanted KidneyConversion DisorderCoronary Artery BypassCytomegalovirus Infection

Showing 15 of 117 indications

Belatacept brand names and reporting trend

Belatacept is sold under the brand name Nulojix.

Brand names

Nulojix3,238

Quarterly reports (20052025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking belatacept with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.