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Aztreonam Side Effects

The most commonly reported side effects of aztreonam include cystic fibrosis, off label use, and pneumonia, based on 19,004 FDA adverse event reports from 2004 to 2025.

Aztreonam side effects

Percentages show how often each reaction appears relative to total reports for aztreonam.

1
Cystic Fibrosis16.2%3,086
2
Off Label Use9.3%1,763
3
Pneumonia7.7%1,461
4
Death7.1%1,349
5
Infective Pulmonary Exacerbation Of Cystic Fibrosis6.5%1,229
6
Infection5.3%1,015
7
Dyspnoea4.3%813
8
Condition Aggravated3.3%636
9
Cough3.3%628
10
Lung Disorder3.2%612
11
Lung Transplant2.9%546
12
Cystic Fibrosis Respiratory Infection Suppression2.7%511
13
Haemoptysis2.2%418
14
Pseudomonas Infection2.2%411
15
Hospitalisation2.1%399

These are voluntary reports and do not establish that aztreonam caused these reactions.

Report severity

89.0%Serious16,910 reports
61.6%Hospitalizations11,711 reports
12.4%Fatal2,358 reports

Seriousness is determined by the reporter, not by OpenClaim.

Aztreonam drug interactions

Other drugs that appear in adverse event reports alongside aztreonam. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Ivacaftor16.4%3,120
2
Elexacaftor-ivacaftor-tezacaftor5.6%1,055
3
Tobramycin5.4%1,023
4
Lumacaftor4.4%829
5
Dornase-alfa3.0%570
6
Vancomycin2.6%493
7
Ciprofloxacin1.6%306
8
Meropenem1.6%301
9
Metronidazole1.0%193
10
Linezolid0.9%165
11
Ceftazidime0.8%160
12
Albuterol0.8%160
13
Daptomycin0.7%139
14
Lipase0.7%137
15
Pancrelipase-amylase0.7%136

Taken alongside

1
Dornase-alfa23.2%4,409
2
Albuterol21.8%4,134
3
Lipase18.7%3,554
4
Pancrelipase-amylase18.2%3,450
5
Protease18.2%3,450
6
Tobramycin14.5%2,758
7
Azithromycin14.2%2,701
8
Fluticasone12.4%2,353
9
Sodium-chloride12.3%2,337
10
Ergocalciferol10.1%1,927
11
Ivacaftor9.1%1,727
12
Omeprazole7.2%1,368
13
Insulin6.7%1,271
14
Montelukast-sodium6.4%1,216
15
Elexacaftor-ivacaftor-tezacaftor5.7%1,086

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports aztreonam side effects

57.0% of aztreonam adverse event reports involve female patients and 40.2% involve male patients. The largest age group is adult at 67%. These figures reflect who reports side effects, not underlying risk.

Sex

Female57.0%
Male40.2%
Unknown2.8%

Age group

< 20.4%
2–117.6%
12–1711.6%
18–6467.2%
65+13.2%

What is aztreonam used for

Conditions and purposes for which patients were taking aztreonam when the adverse event was reported.

Abdominal AbscessAbdominal InfectionAbdominal SepsisAbscessAbscess LimbAcinetobacter InfectionActinic KeratosisAcute Generalised Exanthematous PustulosisAcute Myeloid LeukaemiaAcute Respiratory FailureAdenovirus InfectionAdverse EventAeromonas InfectionAgranulocytosisAlpha-1 Anti-trypsin Deficiency

Showing 15 of 566 indications

Aztreonam brand names and reporting trend

Aztreonam is sold under the brand name Aztreonam.

Brand names

Aztreonam18,848

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking aztreonam with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.