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Avibactam Side Effects

The most commonly reported side effects of avibactam include off label use, drug resistance, and pyrexia, based on 458 FDA adverse event reports from 2013 to 2025. 8.7% of reports found the drug to be ineffective.

Avibactam side effects

Percentages show how often each reaction appears relative to total reports for avibactam.

1
Off Label Use18.1%83
2
Drug Ineffective8.7%40
3
Drug Resistance7.9%36
4
Pyrexia7.4%34
5
Death5.7%26
6
Septic Shock5.0%23
7
Diarrhoea5.0%23
8
Respiratory Failure3.9%18
9
Sepsis3.9%18
10
Nausea3.7%17
11
Product Use In Unapproved Indication3.5%16
12
Pathogen Resistance3.3%15
13
Pneumonia3.1%14
14
Hyperbilirubinaemia3.1%14
15
Cholestasis2.8%13

These are voluntary reports and do not establish that avibactam caused these reactions.

Report severity

79.3%Serious363 reports
35.2%Hospitalizations161 reports
21.0%Fatal96 reports

Seriousness is determined by the reporter, not by OpenClaim.

Avibactam drug interactions

Other drugs that appear in adverse event reports alongside avibactam. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Ceftazidime41.7%191
2
Vancomycin13.3%61
3
Meropenem12.4%57
4
Linezolid6.1%28
5
Aztreonam5.9%27
6
Colistin-sulfate4.8%22
7
Tazobactam-sodium4.8%22
8
Metronidazole4.1%19
9
Amphotericin-b4.1%19
10
Posaconazole3.9%18
11
Tigecycline3.7%17
12
Piperacillin3.7%17
13
Caspofungin-acetate3.3%15
14
Tacrolimus3.1%14
15
Voriconazole3.1%14

Taken alongside

1
Ceftazidime16.2%74
2
Meropenem8.3%38
3
Amikacin-sulfate7.4%34
4
Sodium-chloride7.0%32
5
Aztreonam5.7%26
6
Amphotericin-b5.2%24
7
Ondansetron5.2%24
8
Linezolid5.2%24
9
Levofloxacin5.0%23
10
Acetaminophen4.8%22
11
Vancomycin4.8%22
12
Colistin-sulfate4.6%21
13
Ganciclovir4.4%20
14
Tigecycline4.1%19
15
Dextrose4.1%19

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports avibactam side effects

34.1% of avibactam adverse event reports involve female patients and 44.8% involve male patients. The largest age group is adult at 59%. These figures reflect who reports side effects, not underlying risk.

Sex

Female34.1%
Male44.8%
Unknown21.2%

Age group

< 21.8%
2–112.3%
12–172.9%
18–6458.8%
65+34.2%

What is avibactam used for

Conditions and purposes for which patients were taking avibactam when the adverse event was reported.

Abdominal InfectionAcute Myeloid LeukaemiaAntibiotic TherapyAbdominal InfectionAchromobacter InfectionAcinetobacter InfectionAcinetobacter Test PositiveAnti-infective TherapyAntibiotic TherapyAntifungal TreatmentAspergillus InfectionBacteraemiaBacterial InfectionBacterial Test PositiveBurkholderia Cepacia Complex Infection

Showing 15 of 106 indications

Avibactam brand names and reporting trend

Avibactam is sold under the brand name Emblaveo.

Brand names

Emblaveo387

Quarterly reports (20132025)

20132016202020242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking avibactam with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.