OpenClaim

Avanafil Side Effects

The most commonly reported side effects of avanafil include drug effect decreased, wrong technique in product usage process, and erectile dysfunction, based on 629 FDA adverse event reports from 2005 to 2025. 52.8% of reports found the drug to be ineffective.

Avanafil side effects

Percentages show how often each reaction appears relative to total reports for avanafil.

1
Drug Ineffective52.8%332
2
Drug Effect Decreased6.2%39
3
Wrong Technique In Product Usage Process5.4%34
4
Erectile Dysfunction4.9%31
5
Headache4.0%25
6
Flushing2.7%17
7
Drug Effect Incomplete2.1%13
8
Expired Product Administered2.1%13
9
Eye Inflammation1.9%12
10
Dizziness1.7%11
11
Nausea1.7%11
12
Bladder Cancer1.7%11
13
Fatigue1.6%10
14
Chronic Kidney Disease1.6%10
15
Erection Increased1.4%9

These are voluntary reports and do not establish that avanafil caused these reactions.

Report severity

22.7%Serious143 reports
4.5%Hospitalizations28 reports
0.8%Fatal5 reports

Seriousness is determined by the reporter, not by OpenClaim.

Avanafil drug interactions

Other drugs that appear in adverse event reports alongside avanafil. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Tadalafil4.8%30
2
Sildenafil-citrate4.0%25
3
Atorvastatin-calcium2.5%16
4
Lenalidomide2.1%13
5
Vardenafil-hydrochloride2.1%13
6
Pantoprazole-sodium2.1%13
7
Bisoprolol-fumarate1.9%12
8
Ezetimibe1.6%10
9
Perindopril1.6%10
10
Omeprazole1.4%9
11
Emtricitabine1.1%7
12
Tenofovir1.0%6
13
Testosterone1.0%6
14
Adalimumab0.8%5
15
Risperidone0.8%5

Taken alongside

1
Atorvastatin-calcium8.7%55
2
Aspirin6.5%41
3
Lisinopril6.4%40
4
Amlodipine6.4%40
5
Tadalafil5.6%35
6
Acetaminophen5.2%33
7
Sildenafil-citrate5.1%32
8
Simvastatin4.6%29
9
Omeprazole4.1%26
10
Metoprolol4.0%25
11
Tamsulosin-hydrochloride4.0%25
12
Gabapentin3.7%23
13
Hydrochlorothiazide3.5%22
14
Metformin3.5%22
15
Testosterone3.3%21

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports avanafil side effects

0.5% of avanafil adverse event reports involve female patients and 96.7% involve male patients. The largest age group is adult at 53%. These figures reflect who reports side effects, not underlying risk.

Sex

Female0.5%
Male96.7%
Unknown2.9%

Age group

< 20.0%
2–110.2%
12–170.0%
18–6452.5%
65+47.2%

What is avanafil used for

Conditions and purposes for which patients were taking avanafil when the adverse event was reported.

Blood Pressure MeasurementCardiovascular DisorderDiabetic NeuropathyErectile DysfunctionErectile DysfunctionGenital Disorder MaleHypogonadismIll-defined DisorderPenis DisorderProduct Use IssueProduct Used For Unknown IndicationProduct Used For Unknown IndicationRenal FailureSexual Activity IncreasedSexual Dysfunction

Showing 15 of 17 indications

Avanafil brand names and reporting trend

Avanafil is sold under the brand name Stendra.

Brand names

Stendra69

Quarterly reports (20052025)

2005201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking avanafil with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.