OpenClaim

Avacincaptad Side Effects

The most commonly reported side effects of avacincaptad include intercepted product preparation error, needle issue, and no adverse event, based on 230 FDA adverse event reports from 2023 to 2025.

Avacincaptad side effects

Percentages show how often each reaction appears relative to total reports for avacincaptad.

1
Intercepted Product Preparation Error9.6%22
2
Needle Issue9.1%21
3
No Adverse Event8.3%19
4
Eye Pain7.8%18
5
Vision Blurred7.4%17
6
Visual Impairment7.4%17
7
Off Label Use7.4%17
8
Syringe Issue6.5%15
9
Endophthalmitis6.1%14
10
Intraocular Pressure Increased5.7%13
11
Vitritis5.2%12
12
Eye Inflammation5.2%12
13
Uveitis4.8%11
14
Device Issue4.8%11
15
Vitreous Floaters4.3%10

These are voluntary reports and do not establish that avacincaptad caused these reactions.

Report severity

47.0%Serious108 reports
2.2%Hospitalizations5 reports
1.3%Fatal3 reports

Seriousness is determined by the reporter, not by OpenClaim.

Avacincaptad drug interactions

Other drugs that appear in adverse event reports alongside avacincaptad. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Pegcetacoplan5.7%13
2
Timolol1.3%3
3
Prednisone1.3%3
4
Povidone-iodine0.9%2
5
Ranibizumab0.9%2
6
Cyclosporine0.4%1
7
Semaglutide0.4%1
8
Aflibercept0.4%1
9
Dexamethasone0.4%1
10
Prednisolone0.4%1
11
Dupilumab0.4%1

Taken alongside

1
Aspirin5.2%12
2
Metoprolol4.3%10
3
Lisinopril3.9%9
4
Levothyroxine-sodium3.5%8
5
Atorvastatin-calcium3.5%8
6
Omeprazole3.0%7
7
Faricimab-svoa3.0%7
8
Aflibercept2.6%6
9
Ergocalciferol2.6%6
10
Bevacizumab2.6%6
11
Gabapentin2.2%5
12
Prednisone2.2%5
13
Apixaban2.2%5
14
Losartan-potassium2.2%5
15
Tramadol-hydrochloride1.7%4

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports avacincaptad side effects

50.4% of avacincaptad adverse event reports involve female patients and 25.2% involve male patients. The largest age group is elderly at 93%. These figures reflect who reports side effects, not underlying risk.

Sex

Female50.4%
Male25.2%
Unknown24.3%

Age group

< 20.0%
2–110.0%
12–170.0%
18–647.4%
65+92.6%

What is avacincaptad used for

Conditions and purposes for which patients were taking avacincaptad when the adverse event was reported.

Age-related Macular DegenerationDry Age-related Macular DegenerationDry EyeMacular DegenerationNeovascular Age-related Macular DegenerationProduct Used For Unknown IndicationRetinal DetachmentStargardt^s Disease

Avacincaptad brand names and reporting trend

Avacincaptad is sold under the brand name Izervay.

Brand names

Izervay96

Quarterly reports (20232025)

202320242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking avacincaptad with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.