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Atorvastatin Side Effects

The most commonly reported side effects of atorvastatin include fatigue, diarrhoea, and nausea, based on 495,319 FDA adverse event reports from 2004 to 2025. 4.0% of reports found the drug to be ineffective.

Atorvastatin side effects

Percentages show how often each reaction appears relative to total reports for atorvastatin.

1
Fatigue4.9%24,315
2
Diarrhoea4.2%21,013
3
Nausea4.0%19,752
4
Drug Ineffective4.0%19,687
5
Dyspnoea3.9%19,421
6
Off Label Use3.3%16,464
7
Dizziness3.2%16,051
8
Headache3.0%15,041
9
Pain2.9%14,481
10
Fall2.8%13,760
11
Asthenia2.8%13,689
12
Death2.7%13,182
13
Acute Kidney Injury2.6%12,721
14
Arthralgia2.6%12,716
15
Malaise2.4%11,788

These are voluntary reports and do not establish that atorvastatin caused these reactions.

Report severity

71.3%Serious353,079 reports
33.9%Hospitalizations167,732 reports
8.0%Fatal39,721 reports

Seriousness is determined by the reporter, not by OpenClaim.

Atorvastatin drug interactions

Other drugs that appear in adverse event reports alongside atorvastatin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Lenalidomide3.4%17,009
2
Adalimumab2.8%13,625
3
Aspirin2.7%13,451
4
Omeprazole2.4%11,829
5
Metformin2.3%11,582
6
Amlodipine2.1%10,403
7
Apixaban2.0%9,664
8
Pantoprazole-sodium1.9%9,328
9
Esomeprazole1.7%8,321
10
Rivaroxaban1.5%7,393
11
Lansoprazole1.4%6,763
12
Dupilumab1.4%6,731
13
Pregabalin1.3%6,681
14
Furosemide1.3%6,327
15
Valsartan1.3%6,268

Taken alongside

1
Aspirin25.2%124,759
2
Amlodipine14.0%69,340
3
Metformin13.7%67,861
4
Metoprolol13.5%66,626
5
Furosemide12.4%61,432
6
Levothyroxine-sodium12.3%61,012
7
Acetaminophen12.3%60,895
8
Ergocalciferol11.3%55,905
9
Omeprazole11.1%55,099
10
Lisinopril10.5%52,226
11
Insulin8.3%41,264
12
Pantoprazole-sodium8.3%41,086
13
Albuterol8.2%40,508
14
Gabapentin7.9%39,133
15
Losartan-potassium7.5%37,041

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports atorvastatin side effects

46.9% of atorvastatin adverse event reports involve female patients and 45.4% involve male patients. The largest age group is elderly at 60%. These figures reflect who reports side effects, not underlying risk.

Sex

Female46.9%
Male45.4%
Unknown7.7%

Age group

< 2<0.1%
2–11<0.1%
12–17<0.1%
18–6440.1%
65+59.7%

What is atorvastatin used for

Conditions and purposes for which patients were taking atorvastatin when the adverse event was reported.

Abdominal DiscomfortAbdominal DistensionAbdominal PainAbdominal Pain UpperAccidental Exposure To ProductAcid Reflux (esophageal)AcrochordonAcromegalyAcute Coronary SyndromeAcute Graft Versus Host DiseaseAcute Kidney InjuryAcute Left Ventricular FailureAcute Myocardial InfarctionAcute Promyelocytic LeukaemiaAcute Pulmonary Oedema

Showing 15 of 1,634 indications

Atorvastatin brand names and reporting trend

Atorvastatin is sold under the brand name Atorvaliq.

Brand names

Atorvaliq337,052

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking atorvastatin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.