OpenClaim

Atogepant Side Effects

The most commonly reported side effects of atogepant include migraine, headache, and nausea, based on 5,799 FDA adverse event reports from 2021 to 2025. 12.8% of reports found the drug to be ineffective.

Atogepant side effects

Percentages show how often each reaction appears relative to total reports for atogepant.

1
Migraine18.2%1,058
2
Drug Ineffective12.8%744
3
Headache10.3%599
4
Nausea9.7%561
5
Constipation7.2%418
6
Fatigue6.7%391
7
Dizziness4.2%246
8
Therapy Interrupted3.2%186
9
Decreased Appetite2.8%163
10
Off Label Use2.8%160
11
Pain2.6%152
12
Vomiting2.6%148
13
Therapeutic Product Effect Incomplete2.4%140
14
Anxiety2.2%129
15
Weight Decreased2.2%129

These are voluntary reports and do not establish that atogepant caused these reactions.

Report severity

32.0%Serious1,856 reports
7.9%Hospitalizations459 reports
1.1%Fatal61 reports

Seriousness is determined by the reporter, not by OpenClaim.

Atogepant drug interactions

Other drugs that appear in adverse event reports alongside atogepant. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Ubrogepant3.3%193
2
Onabotulinumtoxina3.2%183
3
Eptinezumab-jjmr2.5%144
4
Dupilumab1.8%103
5
Rimegepant1.7%99
6
Sodium-oxybate1.5%87
7
Calcium-oxybate0.9%53
8
Magnesium-oxybate0.9%53
9
Potassium-oxybate0.9%53
10
Erenumab-aooe0.8%47
11
Galcanezumab-gnlm0.8%45
12
Topiramate0.7%38
13
Fremanezumab-vfrm0.6%32
14
Acetaminophen0.4%26
15
Adalimumab0.3%20

Taken alongside

1
Acetaminophen5.2%304
2
Ergocalciferol5.1%295
3
Ubrogepant5.0%288
4
Topiramate4.3%251
5
Gabapentin4.1%238
6
Levothyroxine-sodium3.8%222
7
Rimegepant3.6%211
8
Ondansetron3.6%207
9
Omeprazole3.2%184
10
Albuterol3.1%180
11
Sumatriptan2.7%156
12
Aspirin2.7%156
13
Famotidine2.5%147
14
Montelukast-sodium2.5%145
15
Cetirizine-hydrochloride2.5%143

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports atogepant side effects

75.1% of atogepant adverse event reports involve female patients and 11.8% involve male patients. The largest age group is adult at 82%. These figures reflect who reports side effects, not underlying risk.

Sex

Female75.1%
Male11.8%
Unknown13.0%

Age group

< 2<0.1%
2–11<0.1%
12–170.5%
18–6482.0%
65+17.5%

What is atogepant used for

Conditions and purposes for which patients were taking atogepant when the adverse event was reported.

Abdominal DiscomfortAdverse Drug ReactionBipolar DisorderBrain NeoplasmCovid-19Chronic Inflammatory Demyelinating PolyradiculoneuropathyCluster HeadacheColitis UlcerativeComplex Regional Pain SyndromeConstipationCrohn^s DiseaseDecreased AppetiteDementiaDermatitis AtopicDiarrhoea

Showing 15 of 64 indications

Atogepant brand names and reporting trend

Atogepant is sold under the brand name Qulipta.

Brand names

Qulipta658

Quarterly reports (20212025)

202220242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking atogepant with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.