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Artemether Side Effects

The most commonly reported side effects of artemether include vomiting, off label use, and pyrexia, based on 288 FDA adverse event reports from 2004 to 2025. 4.5% of reports found the drug to be ineffective.

Artemether side effects

Percentages show how often each reaction appears relative to total reports for artemether.

1
Vomiting6.3%18
2
Off Label Use5.6%16
3
Pyrexia5.2%15
4
Drug Exposure During Pregnancy4.9%14
5
Asthenia4.9%14
6
Drug Ineffective4.5%13
7
Dyspnoea3.8%11
8
Headache3.8%11
9
Malaise3.8%11
10
Malaria3.5%10
11
Maternal Exposure During Pregnancy3.5%10
12
Pyrexia3.1%9
13
Dizziness3.1%9
14
Fatigue3.1%9
15
Dyspnoea3.1%9

These are voluntary reports and do not establish that artemether caused these reactions.

Report severity

86.1%Serious248 reports
33.0%Hospitalizations95 reports
10.8%Fatal31 reports

Seriousness is determined by the reporter, not by OpenClaim.

Artemether drug interactions

Other drugs that appear in adverse event reports alongside artemether. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Lumefantrine57.6%166
2
Amoxicillin4.5%13
3
Azithromycin3.5%10
4
Valbenazine3.1%9
5
Atovaquone2.4%7
6
Metronidazole2.4%7
7
Ciprofloxacin2.1%6
8
Proguanil-hydrochloride1.7%5
9
Acetaminophen1.7%5
10
Clavulanate-potassium1.7%5
11
Quinine-sulfate1.7%5
12
Naproxen1.7%5
13
Sodium-oxybate1.4%4
14
Hydroxychloroquine-sulfate1.4%4
15
Rotigotine1.4%4

Taken alongside

1
Acetaminophen13.9%40
2
Lumefantrine13.5%39
3
Metronidazole5.6%16
4
Ergocalciferol4.2%12
5
Amoxicillin3.5%10
6
Omeprazole3.5%10
7
Ascorbic-acid3.5%10
8
Gabapentin3.1%9
9
Ceftriaxone-sodium2.8%8
10
Atovaquone2.4%7
11
Artesunate2.4%7
12
Nystatin2.4%7
13
Diazepam2.1%6
14
Furosemide2.1%6
15
Quinine-sulfate2.1%6

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports artemether side effects

52.1% of artemether adverse event reports involve female patients and 37.2% involve male patients. The largest age group is adult at 66%. These figures reflect who reports side effects, not underlying risk.

Sex

Female52.1%
Male37.2%
Unknown10.8%

Age group

< 23.7%
2–1114.8%
12–177.9%
18–6466.1%
65+7.4%

What is artemether used for

Conditions and purposes for which patients were taking artemether when the adverse event was reported.

Antiretroviral TherapyBabesiosisBabesiosisCerebral MalariaCovid-19CamptocormiaCerebral MalariaDepressionDyskinesiaDystoniaExtrapyramidal DisorderGiant Cell ArteritisHypersensitivityHyperthermiaInfection

Showing 15 of 32 indications

Artemether brand names and reporting trend

Artemether is sold under the brand name Coartem.

Brand names

Coartem105

Quarterly reports (20042025)

20042010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking artemether with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.