The most commonly reported side effects of aprocitentan include haemoglobin decreased, cough, and septic shock, based on 20 FDA adverse event reports from 2004 to 2025.
Percentages show how often each reaction appears relative to total reports for aprocitentan.
These are voluntary reports and do not establish that aprocitentan caused these reactions.
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Other drugs that appear in adverse event reports alongside aprocitentan. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.
Also suspected
Taken alongside
Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.
50.0% of aprocitentan adverse event reports involve female patients and 50.0% involve male patients. The largest age group is elderly at 50%. These figures reflect who reports side effects, not underlying risk.
Sex
Age group
Conditions and purposes for which patients were taking aprocitentan when the adverse event was reported.
Aprocitentan is sold under the brand name Tryvio.
An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.
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