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Aminocaproic Side Effects

The most commonly reported side effects of aminocaproic include pain, renal failure, and injury, based on 1,597 FDA adverse event reports from 2004 to 2025. 4.2% of reports found the drug to be ineffective.

Aminocaproic side effects

Percentages show how often each reaction appears relative to total reports for aminocaproic.

1
Pain10.6%170
2
Renal Failure10.2%163
3
Injury9.6%154
4
Unevaluable Event9.3%149
5
Anxiety9.3%148
6
Haemorrhage8.4%134
7
Fear8.2%131
8
Renal Injury7.8%125
9
Emotional Distress7.4%118
10
Death6.8%109
11
Renal Impairment6.4%102
12
Anhedonia6.4%102
13
Stress6.2%99
14
Multi-organ Failure5.8%92
15
Off Label Use5.1%82

These are voluntary reports and do not establish that aminocaproic caused these reactions.

Report severity

78.5%Serious1,254 reports
37.9%Hospitalizations606 reports
22.5%Fatal359 reports

Seriousness is determined by the reporter, not by OpenClaim.

Aminocaproic drug interactions

Other drugs that appear in adverse event reports alongside aminocaproic. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Aprotinin11.2%179
2
Emicizumab7.5%120
3
Lenalidomide3.7%59
4
Romiplostim3.6%58
5
Omega3.2%51
6
Heparin2.7%43
7
Venetoclax2.2%35
8
Azacitidine1.8%29
9
Eltrombopag1.7%27
10
Cytarabine1.6%26
11
Sodium-oxybate1.5%24
12
Ruxolitinib1.3%21
13
Fostamatinib-disodium1.3%21
14
Prednisone1.2%19
15
Rituximab1.2%19

Taken alongside

1
Acetaminophen16.0%255
2
Furosemide15.0%240
3
Heparin14.9%238
4
Insulin10.5%167
5
Metoprolol10.2%163
6
Potassium-chloride10.1%161
7
Ondansetron10.0%159
8
Pantoprazole-sodium9.6%154
9
Fentanyl9.5%151
10
Epinephrine9.1%145
11
Midazolam8.7%139
12
Acyclovir8.6%137
13
Vancomycin8.4%134
14
Levothyroxine-sodium8.3%132
15
Sodium-chloride8.3%132

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports aminocaproic side effects

33.8% of aminocaproic adverse event reports involve female patients and 58.1% involve male patients. The largest age group is adult at 41%. These figures reflect who reports side effects, not underlying risk.

Sex

Female33.8%
Male58.1%
Unknown8.1%

Age group

< 24.4%
2–1115.5%
12–177.9%
18–6441.0%
65+31.1%

What is aminocaproic used for

Conditions and purposes for which patients were taking aminocaproic when the adverse event was reported.

Abdominal PainAcquired HaemophiliaAcquired Haemophilia With Anti Fviii, Xi, Or XiiiAnaemiaAnaesthesiaAntibiotic ProphylaxisAnticoagulant TherapyAortic SurgeryAortic Valve RepairAortic Valve ReplacementAplastic AnaemiaAsthenopiaAcquired Von Willebrand^s DiseaseAcquired Factor Viii DeficiencyAcute Lymphocytic Leukaemia

Showing 15 of 156 indications

Aminocaproic brand names and reporting trend

Aminocaproic is sold under the brand name Aminocaproic.

Brand names

Aminocaproic780

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking aminocaproic with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.