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Alogliptin Side Effects

The most commonly reported side effects of alogliptin include diarrhoea, nausea, and vomiting, based on 4,332 FDA adverse event reports from 2004 to 2025. 2.5% of reports found the drug to be ineffective.

Alogliptin side effects

Percentages show how often each reaction appears relative to total reports for alogliptin.

1
Diarrhoea4.2%180
2
Nausea3.8%166
3
Vomiting3.2%138
4
Acute Kidney Injury2.8%121
5
Rash2.7%116
6
Malaise2.6%111
7
Blood Glucose Increased2.5%110
8
Drug Ineffective2.5%110
9
Dyspnoea2.5%109
10
Pemphigoid2.4%106
11
Pneumonia2.4%102
12
Dizziness2.3%99
13
Decreased Appetite2.2%96
14
Headache2.2%95
15
Fatigue2.1%93

These are voluntary reports and do not establish that alogliptin caused these reactions.

Report severity

82.5%Serious3,573 reports
43.8%Hospitalizations1,897 reports
9.5%Fatal410 reports

Seriousness is determined by the reporter, not by OpenClaim.

Alogliptin drug interactions

Other drugs that appear in adverse event reports alongside alogliptin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Metformin8.0%347
2
Pioglitazone-hydrochloride6.8%296
3
Empagliflozin2.2%95
4
Dapagliflozin1.9%82
5
Insulin1.8%77
6
Glimepiride1.8%76
7
Amlodipine1.7%75
8
Canagliflozin1.6%68
9
Vedolizumab1.5%67
10
Pantoprazole-sodium1.5%63
11
Lenalidomide1.3%58
12
Atorvastatin-calcium1.3%56
13
Ciclesonide1.2%51
14
Rosuvastatin1.1%49
15
Rivaroxaban1.1%48

Taken alongside

1
Metformin22.3%965
2
Atorvastatin-calcium15.9%689
3
Amlodipine14.4%622
4
Aspirin14.0%608
5
Glimepiride10.9%473
6
Insulin9.4%407
7
Furosemide8.3%359
8
Hydrochlorothiazide7.4%322
9
Omeprazole6.8%295
10
Rosuvastatin6.7%291
11
Lansoprazole6.3%274
12
Pioglitazone-hydrochloride6.3%272
13
Acetaminophen6.0%262
14
Levothyroxine-sodium5.5%237
15
Simvastatin4.4%192

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports alogliptin side effects

39.2% of alogliptin adverse event reports involve female patients and 53.0% involve male patients. The largest age group is elderly at 63%. These figures reflect who reports side effects, not underlying risk.

Sex

Female39.2%
Male53.0%
Unknown7.8%

Age group

< 20.3%
2–110.1%
12–170.0%
18–6436.9%
65+62.7%

What is alogliptin used for

Conditions and purposes for which patients were taking alogliptin when the adverse event was reported.

Adverse Drug ReactionBenign Prostatic HyperplasiaBlood CholesterolBlood DisorderBlood Glucose AbnormalBlood Glucose DecreasedBlood Glucose FluctuationBlood Glucose IncreasedBlood Pressure AbnormalBlood Glucose AbnormalBlood Glucose DecreasedBlood Glucose IncreasedCardiac Failure CongestiveCerebral HaemorrhageCerebrovascular Accident

Showing 15 of 67 indications

Alogliptin brand names and reporting trend

Alogliptin is sold under brand names including Alogliptin; Metformin Hydrochloride, Oseni.

Brand names

Alogliptin; Metformin Hydrochloride1,868
Oseni314

Quarterly reports (20042025)

2004201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking alogliptin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.