The most commonly reported side effects of aflibercept include death, visual impairment, and off label use, based on 31,953 FDA adverse event reports from 2006 to 2025. 3.6% of reports found the drug to be ineffective.
Percentages show how often each reaction appears relative to total reports for aflibercept.
These are voluntary reports and do not establish that aflibercept caused these reactions.
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Other drugs that appear in adverse event reports alongside aflibercept. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.
Also suspected
Taken alongside
Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.
19.7% of aflibercept adverse event reports involve female patients and 19.0% involve male patients. The largest age group is elderly at 68%. These figures reflect who reports side effects, not underlying risk.
Sex
Age group
Conditions and purposes for which patients were taking aflibercept when the adverse event was reported.
Showing 15 of 519 indications
Aflibercept is sold under several brand names including Eylea Hd, Zaltrap, Opuviz.
An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.
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