OpenClaim

Acrivastine Side Effects

The most commonly reported side effects of acrivastine include off label use, nausea, and pneumonia, based on 1,012 FDA adverse event reports from 2004 to 2025. 10.1% of reports found the drug to be ineffective.

Acrivastine side effects

Percentages show how often each reaction appears relative to total reports for acrivastine.

1
Off Label Use18.8%190
2
Nausea16.9%171
3
Pneumonia12.6%128
4
Condition Aggravated12.5%126
5
Pruritus11.8%119
6
Drug Ineffective10.1%102
7
Fatigue9.9%100
8
Vomiting9.8%99
9
Hepatic Enzyme Increased9.4%95
10
Rash9.2%93
11
Pain8.9%90
12
Chronic Obstructive Pulmonary Disease8.3%84
13
Gastrooesophageal Reflux Disease8.3%84
14
Cholelithiasis8.1%82
15
Headache8.1%82

These are voluntary reports and do not establish that acrivastine caused these reactions.

Report severity

72.3%Serious732 reports
32.3%Hospitalizations327 reports
5.7%Fatal58 reports

Seriousness is determined by the reporter, not by OpenClaim.

Acrivastine drug interactions

Other drugs that appear in adverse event reports alongside acrivastine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Rituximab13.8%140
2
Montelukast-sodium10.4%105
3
Acetaminophen9.3%94
4
Lenalidomide8.8%89
5
Clonazepam8.7%88
6
Prednisone8.7%88
7
Diazepam7.6%77
8
Quetiapine-fumarate7.5%76
9
Olanzapine7.3%74
10
Tipranavir7.2%73
11
Carbamazepine7.1%72
12
Tiotropium-bromide7.0%71
13
Trazodone-hydrochloride7.0%71
14
Mepolizumab7.0%71
15
Fluticasone6.9%70

Taken alongside

1
Acetaminophen38.2%387
2
Diphenhydramine19.9%201
3
Albuterol16.8%170
4
Methylprednisolone15.8%160
5
Ergocalciferol15.5%157
6
Prednisone14.9%151
7
Aspirin14.4%146
8
Atorvastatin-calcium11.6%117
9
Ondansetron11.5%116
10
Dexamethasone11.3%114
11
Loperamide-hydrochloride11.0%111
12
Montelukast-sodium10.9%110
13
Cetirizine-hydrochloride10.4%105
14
Sertraline-hydrochloride10.3%104
15
Acyclovir9.6%97

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports acrivastine side effects

61.8% of acrivastine adverse event reports involve female patients and 28.3% involve male patients. The largest age group is adult at 60%. These figures reflect who reports side effects, not underlying risk.

Sex

Female61.8%
Male28.3%
Unknown10.0%

Age group

< 20.2%
2–111.7%
12–172.1%
18–6459.7%
65+36.3%

What is acrivastine used for

Conditions and purposes for which patients were taking acrivastine when the adverse event was reported.

AgitationAnxietyAsthmaAdverse Drug ReactionAllergy To ChemicalsAnaphylactic ReactionAntiallergic TherapyApplication Site ReactionArthropod StingAsthmaChemotherapy Side Effect ProphylaxisChronic Spontaneous UrticariaChemotherapyChronic Spontaneous UrticariaDrug Use For Unknown Indication

Showing 15 of 63 indications

Acrivastine brand names and reporting trend

Acrivastine is sold under the brand name Semprex-d.

Brand names

Semprex-d1,005

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking acrivastine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.