OpenClaim

Abiraterone Side Effects

The most commonly reported side effects of abiraterone include death, fatigue, and prostatic specific antigen increased, based on 40,872 FDA adverse event reports from 2008 to 2025. 4.9% of reports found the drug to be ineffective.

Abiraterone side effects

Percentages show how often each reaction appears relative to total reports for abiraterone.

1
Death15.1%6,180
2
Fatigue6.3%2,595
3
Drug Ineffective4.9%1,991
4
Prostatic Specific Antigen Increased4.8%1,979
5
Therapy Cessation3.9%1,583
6
Hot Flush3.5%1,447
7
Asthenia3.1%1,273
8
Disease Progression3.0%1,225
9
Hospitalisation2.7%1,084
10
Off Label Use2.6%1,066
11
Nausea2.5%1,007
12
Diarrhoea2.3%955
13
Fall2.3%941
14
Prostate Cancer2.1%864
15
Dizziness2.0%833

These are voluntary reports and do not establish that abiraterone caused these reactions.

Report severity

68.5%Serious27,996 reports
27.0%Hospitalizations11,041 reports
20.6%Fatal8,432 reports

Seriousness is determined by the reporter, not by OpenClaim.

Abiraterone drug interactions

Other drugs that appear in adverse event reports alongside abiraterone. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Prednisone9.4%3,836
2
Enzalutamide5.5%2,263
3
Prednisolone3.6%1,488
4
Leuprolide3.2%1,326
5
Relugolix2.7%1,123
6
Docetaxel2.4%971
7
Denosumab1.6%661
8
Bicalutamide1.2%480
9
Cabazitaxel1.1%453
10
Degarelix-acetate0.8%322
11
Goserelin0.7%302
12
Apalutamide0.7%289
13
Dexamethasone0.7%288
14
Zoledronic-acid0.7%288
15
Olaparib0.7%266

Taken alongside

1
Prednisone18.0%7,347
2
Leuprolide5.9%2,429
3
Aspirin5.8%2,363
4
Ergocalciferol4.9%1,996
5
Atorvastatin-calcium4.8%1,966
6
Tamsulosin-hydrochloride4.7%1,904
7
Amlodipine4.6%1,882
8
Acetaminophen4.3%1,775
9
Prednisolone4.1%1,689
10
Metoprolol3.6%1,461
11
Calcium3.2%1,314
12
Lisinopril3.2%1,305
13
Metformin3.1%1,281
14
Omeprazole3.1%1,274
15
Furosemide2.8%1,143

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports abiraterone side effects

0.6% of abiraterone adverse event reports involve female patients and 92.9% involve male patients. The largest age group is elderly at 84%. These figures reflect who reports side effects, not underlying risk.

Sex

Female0.6%
Male92.9%
Unknown6.5%

Age group

< 2<0.1%
2–11<0.1%
12–17<0.1%
18–6415.4%
65+84.5%

What is abiraterone used for

Conditions and purposes for which patients were taking abiraterone when the adverse event was reported.

Abdominal PainAccidental Exposure To ProductAcute Myeloid LeukaemiaAdenocarcinomaAdrenogenital SyndromeAdverse EventAnaemiaAnal CancerAntiandrogen TherapyAnxiety DisorderArthropathyAtrial FibrillationAcute Kidney InjuryAdenocarcinomaAdenocarcinoma Metastatic

Showing 15 of 274 indications

Abiraterone brand names and reporting trend

Abiraterone is sold under the brand name Akeega.

Brand names

Akeega15,209

Quarterly reports (20082025)

2010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking abiraterone with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.