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Abacavir Side Effects

The most commonly reported side effects of abacavir include pain, anxiety, and emotional distress, based on 21,677 FDA adverse event reports from 2004 to 2025.

Abacavir side effects

Percentages show how often each reaction appears relative to total reports for abacavir.

1
Pain8.2%1,775
2
Anxiety6.2%1,347
3
Emotional Distress5.8%1,266
4
Anhedonia5.2%1,138
5
Chronic Kidney Disease4.3%941
6
Exposure During Pregnancy4.3%940
7
Nausea4.2%900
8
Product Dose Omission Issue4.0%859
9
Fatigue3.8%830
10
Pyrexia3.8%823
11
Foetal Exposure During Pregnancy3.7%807
12
Headache3.6%786
13
Renal Failure3.5%759
14
Rash3.3%714
15
Off Label Use3.2%700

These are voluntary reports and do not establish that abacavir caused these reactions.

Report severity

79.2%Serious17,179 reports
28.3%Hospitalizations6,133 reports
8.7%Fatal1,885 reports

Seriousness is determined by the reporter, not by OpenClaim.

Abacavir drug interactions

Other drugs that appear in adverse event reports alongside abacavir. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Lamivudine58.8%12,740
2
Dolutegravir30.4%6,586
3
Ritonavir19.8%4,282
4
Tenofovir19.7%4,269
5
Zidovudine13.1%2,844
6
Emtricitabine12.8%2,768
7
Efavirenz11.5%2,499
8
Lopinavir8.2%1,782
9
Raltegravir-potassium7.9%1,708
10
Darunavir7.8%1,682
11
Atazanavir-sulfate7.7%1,675
12
Nevirapine7.0%1,509
13
Didanosine5.1%1,098
14
Stavudine5.0%1,078
15
Rilpivirine3.8%823

Taken alongside

1
Lamivudine24.6%5,322
2
Ritonavir12.8%2,782
3
Dolutegravir12.0%2,600
4
Tenofovir8.9%1,938
5
Emtricitabine6.6%1,438
6
Raltegravir-potassium5.6%1,214
7
Zidovudine5.6%1,206
8
Lopinavir5.5%1,198
9
Atazanavir-sulfate4.8%1,033
10
Efavirenz4.7%1,027
11
Darunavir4.6%1,001
12
Sulfamethoxazole4.5%976
13
Acetaminophen4.4%950
14
Trimethoprim4.0%865
15
Aspirin3.7%808

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports abacavir side effects

27.6% of abacavir adverse event reports involve female patients and 56.2% involve male patients. The largest age group is adult at 84%. These figures reflect who reports side effects, not underlying risk.

Sex

Female27.6%
Male56.2%
Unknown16.2%

Age group

< 23.4%
2–112.1%
12–171.7%
18–6484.2%
65+8.6%

What is abacavir used for

Conditions and purposes for which patients were taking abacavir when the adverse event was reported.

Acquired Immunodeficiency SyndromeAcute Hiv InfectionAcute Kidney InjuryAicardi^s SyndromeAidsAnaemiaAnal CancerAnalgesic TherapyAntiretroviral TherapyAntiviral ProphylaxisAntiviral TreatmentAnxietyArthritisAsthmaAsymptomatic Hiv Infection

Showing 15 of 193 indications

Abacavir brand names and reporting trend

Abacavir is sold under brand names including Epzicom, Triumeq, Dolutegravir Sodium And Abacavir Sulfate And Lamivudine.

Brand names

Epzicom7,196
Triumeq2,326
Dolutegravir Sodium And Abacavir Sulfate And Lamivudine5

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking abacavir with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.